Publication Type
Journal Article
Version
publishedVersion
Publication Date
1-2022
Abstract
Objectives: Understanding factors influencing inappropriate antibiotic use can guide the design of interventions to improve antibiotic practices and reduce antimicrobial resistance (AMR). Methods: A nationally representative cross-sectional survey (N = 2004) was conducted between November 2020 and January 2021. Knowledge of antibiotic use and AMR using the World Health Organization’s Multi-Country AMR Survey questionnaire, and antibiotic practices were examined. Multivariable logistic regression was performed to identify factors associated with inappropriate antibiotic use and examine effect measure modifications. Results: After adjusting for potential confounding, poor knowledge of antibiotic use was associated with a 3x increased odds of inappropriate antibiotic use in adults aged ≥50 years (aOR 3.11, 95% CI [2.24–4.32]), 5× increased odds in those aged 35–49 years (aOR 4.88, 95% CI [3.32–7.16]), and 7× increased odds in those aged 21–34 years (aOR 6.58, 95% CI [4.19–10.33]). While there was no statistically significant association in adults aged ≥50 years, poor knowledge of AMR increased the odds of inappropriate antibiotic use by 4 times in adults aged 35–49 years (aOR 3.73, 95% CI [1.53–9.11]) and 5 times in those aged 21–34 years (aOR 4.90, 95% CI [1.84–13.02]). Conclusions: Targeted educational interventions for specific age groups are needed in conjunction with empowering the public with knowledge of antibiotic use and AMR.
Keywords
antimicrobial resistance, public knowledge, inappropriate antibiotic use, populationbased survey, effect modification
Discipline
Chemicals and Drugs | Community-Based Research | Health and Medical Administration
Research Areas
Sociology
Publication
Antibiotics
Volume
11
Issue
47
First Page
1
Last Page
14
ISSN
2079-6382
Identifier
10.3390/antibiotics11010047
Publisher
MDPI
Citation
GUO, Huiling, HILDON, Zoe Jane-Lara, LYE, David Chien Boon, STRAUGHAN, Paulin Tay, & CHOW, Angela.(2022). The associations between poor antibiotic and antimicrobial resistance knowledge and inappropriate antibiotic use in the general population are modified by age. Antibiotics, 11(47), 1-14.
Available at: https://ink.library.smu.edu.sg/soss_research/3483
Copyright Owner and License
Authors
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Additional URL
https://doi.org/10.3390/antibiotics11010047
Included in
Chemicals and Drugs Commons, Community-Based Research Commons, Health and Medical Administration Commons