Publication Type
Journal Article
Version
acceptedVersion
Publication Date
2-2025
Abstract
Objective: This paper aims to investigate the key factors, including demographics, socioeconomics, physical wellbeing, lifestyle, daily activities and loneliness that can impact depressive symptoms in the middle-aged and elderly population using machine learning techniques. By identifying the most important predictors of depressive symptoms through the analysis, the findings can have important implications for early depression detection and intervention. Participants: For our cross-sectional study, we recruited a total of 976 volunteers, with a specific focus on individuals aged 50 and above. Each participant was requested to provide their demographic, socioeconomic information and undergo several physical health tests. Additionally, they were asked to respond to questionnaires that assessed their mental well-being. Furthermore, participants were requested to maintain an activity log for a continuous 14-day period, starting from the day after they signed up. They had the option to use either a provided mobile application or paper to record their activities. Methods: We evaluated multiple machine learning models to find the best-performing one. Subsequently, we conducted post-hoc analysis to extract the variable significance from the selected model to gain deeper insights into the factors influencing depression. Results: Logistic Regression was chosen as it exhibited superior performance across other models, with AUC of 0.807 f 0.038, accuracy of 0.798 f 0.048, specificity of 0.795 f 0.061, sensitivity of 0.819 f 0.097, NPV of 0.972 f 0.013 and PPV of 0.359 f 0.064. The top influential predictors identified in the model included loneliness, health indicator (i.e. frailty, eyesight, functional mobility), time spent on activities (i.e. staying home, doing exercises and visiting friends) and perceived income adequacy. Conclusion: These findings have the potential to identify individuals at risk of depression and prioritize interventions based on the influential factors. The amount of time dedicated to daily activities emerges as a significant indicator of depression risk among middle-aged and elderly individuals, along with loneliness, physical health indicators and perceived income adequacy.
Keywords
Depression, Demographics, socioeconomics, physical well-being, lifestyle, daily activities and loneliness, Machine learning, Prediction model, Regression model
Discipline
Databases and Information Systems | Gerontology | Numerical Analysis and Scientific Computing
Research Areas
Data Science and Engineering
Publication
Archives of Gerontology and Geriatrics
Volume
129
First Page
1
Last Page
9
ISSN
0167-4943
Identifier
10.1016/j.archger.2024.105647
Publisher
Elsevier
Citation
TRAN, Ngoc Doan Thu; TAN, Yi Zhen; LIN, Sapphire; ZHAO, Fang; NG, Yee Sien; MA, Dong; KO, Jeonggil; and BALAN, Rajesh Krishna.
Exploring key factors influencing depressive symptoms among middle-aged and elderly adult population: A machine learning-based method. (2025). Archives of Gerontology and Geriatrics. 129, 1-9.
Available at: https://ink.library.smu.edu.sg/sis_research/9718
Copyright Owner and License
Authors
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Additional URL
https://doi.org/10.1016/j.archger.2024.105647
Included in
Databases and Information Systems Commons, Gerontology Commons, Numerical Analysis and Scientific Computing Commons